Table 5.
Detailed results of all PCA runs with respect to the second test, i.e. the identification of the 31 unknown mice. Mice in rows #1-20 are WT, whereas mice in rows #21-31 are R6/2
PCA Results for Test 2 | ||||
---|---|---|---|---|
Unknown Subject | First Principal Component (PC1) Score | |||
PCA Covariance Matrix | PCA Correlation Matrix | |||
Standard | ROC-Supervised | Standard | ROC-Supervised | |
1 | 0.13167 | 0.61446 | 0.40658 | 0.78912 |
2 | 0.59647 | 0.32887 | 0.62741 | 0.34816 |
3 | 0.61650 | 0.58706 | 0.67466 | 0.68506 |
4 | 0.27976 | 0.64139 | 0.48024 | 0.84950 |
5 | 0.26657 | 0.93238 | 0.56482 | 1.20830 |
6 | 0.64921 | 0.99697 | 0.72184 | 1.21220 |
7 | 0.58748 | 0.82755 | 0.68411 | 0.97334 |
8 | 0.45766 | 0.89058 | 0.67364 | 1.03990 |
9 | 0.43063 | 0.94261 | 0.71080 | 1.09190 |
10 | 0.76189 | 1.08260 | 1.08250 | 1.24480 |
11 | 0.40067 | 1.03740 | 0.74022 | 1.21150 |
12 | 0.71320 | 1.24290 | 1.08390 | 1.49750 |
13 | 0.44182 | 1.16940 | 0.77265 | 1.37920 |
14 | 0.40866 | 1.15300 | 0.79191 | 1.28990 |
15 | 0.48321 | 0.77448 | 0.69302 | 0.97603 |
16 | 0.28809 | 0.76857 | 0.55896 | 0.92809 |
17 | 0.81518 | 1.01340 | 1.02390 | 1.19510 |
18 | 0.25073 | 0.54776 | 0.59821 | 0.55057 |
19 | 0.23476 | 1.01100 | 0.62662 | 1.23000 |
20 | 0.73047 | 0.95328 | 0.97916 | 1.13380 |
21 | -0.89293 | -1.15940 | -0.78696 | -1.43120 |
22 | -0.91048 | -1.02050 | -1.14860 | -1.41420 |
23 | -1.78630 | -1.77620 | -1.76590 | -2.02740 |
24 | -1.03060 | -1.68840 | -1.29770 | -2.03200 |
25 | -1.24270 | -1.79300 | -1.43730 | -2.14990 |
26 | 0.33614 | -0.94422 | -0.04884 | -1.33740 |
27 | -1.11610 | -1.51380 | -1.50130 | -1.82760 |
28 | 0.61648 | -0.01065 | 0.36699 | -0.10788 |
29 | 0.11753 | -0.30609 | 0.03627 | -0.47616 |
30 | 0.88638 | -0.31285 | 0.41756 | -0.51304 |
31 | -0.13088 | -0.27708 | -0.27506 | -0.37472 |
Only the ROC-supervised PCA (both with the covariance and the correlation matrix) diagnosed/identified correctly all of the 31 unknown mice. All of the WT mice (rows # 1-20) have positive PC1 scores, whereas all of the R6/2 mice (rows # 21-31) have negative PC1 scores.