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. 2011 Feb 3;3(2):180–196.

Table 5.

Detailed results of all PCA runs with respect to the second test, i.e. the identification of the 31 unknown mice. Mice in rows #1-20 are WT, whereas mice in rows #21-31 are R6/2

PCA Results for Test 2

Unknown Subject First Principal Component (PC1) Score

PCA Covariance Matrix PCA Correlation Matrix


Standard ROC-Supervised Standard ROC-Supervised
1 0.13167 0.61446 0.40658 0.78912
2 0.59647 0.32887 0.62741 0.34816
3 0.61650 0.58706 0.67466 0.68506
4 0.27976 0.64139 0.48024 0.84950
5 0.26657 0.93238 0.56482 1.20830
6 0.64921 0.99697 0.72184 1.21220
7 0.58748 0.82755 0.68411 0.97334
8 0.45766 0.89058 0.67364 1.03990
9 0.43063 0.94261 0.71080 1.09190
10 0.76189 1.08260 1.08250 1.24480
11 0.40067 1.03740 0.74022 1.21150
12 0.71320 1.24290 1.08390 1.49750
13 0.44182 1.16940 0.77265 1.37920
14 0.40866 1.15300 0.79191 1.28990
15 0.48321 0.77448 0.69302 0.97603
16 0.28809 0.76857 0.55896 0.92809
17 0.81518 1.01340 1.02390 1.19510
18 0.25073 0.54776 0.59821 0.55057
19 0.23476 1.01100 0.62662 1.23000
20 0.73047 0.95328 0.97916 1.13380
21 -0.89293 -1.15940 -0.78696 -1.43120
22 -0.91048 -1.02050 -1.14860 -1.41420
23 -1.78630 -1.77620 -1.76590 -2.02740
24 -1.03060 -1.68840 -1.29770 -2.03200
25 -1.24270 -1.79300 -1.43730 -2.14990
26 0.33614 -0.94422 -0.04884 -1.33740
27 -1.11610 -1.51380 -1.50130 -1.82760
28 0.61648 -0.01065 0.36699 -0.10788
29 0.11753 -0.30609 0.03627 -0.47616
30 0.88638 -0.31285 0.41756 -0.51304
31 -0.13088 -0.27708 -0.27506 -0.37472

Only the ROC-supervised PCA (both with the covariance and the correlation matrix) diagnosed/identified correctly all of the 31 unknown mice. All of the WT mice (rows # 1-20) have positive PC1 scores, whereas all of the R6/2 mice (rows # 21-31) have negative PC1 scores.