TABLE 2.
Total protein and calcium intakes, range of estimated NEAP, and multivariable-adjusted femoral neck and lumbar spine BMD for quartiles of estimated NEAP in Framingham Original Cohort men and women1,2
| NEAP quartile |
|||||
| 1 | 2 | 3 | 4 | P-trend | |
| Men | |||||
| n | 93 | 96 | 94 | 88 | |
| Total protein,1g/d | 57 ± 20 | 67 ± 22 | 75 ± 24 | 79 ± 25 | |
| Total calcium,1mg/d | 717 ± 377 | 756 ± 398 | 819 ± 411 | 696 ± 348 | |
| Estimated NEAP range, mEq/d | 8.32, 31.24 | 31.41, 39.28 | 39.35, 47.65 | 47.68, 83.60 | |
| Femoral neck BMD,22 | 0.885 ± 0.018 | 0.853 ± 0.017 | 0.844 ± 0.017 | 0.842 ± 0.017 | 0.04 |
| L2-L4 BMD,2g/cm2 | 1.276 ± 0.035 | 1.282 ± 0.034 | 1.298 ± 0.034 | 1.251 ± 0.035 | 0.56 |
| Women | |||||
| n | 148 | 148 | 145 | 146 | |
| Total protein,1g/d | 56 ± 20 | 67 ± 22 | 73 ± 26 | 72 ± 26 | |
| Total calcium,1mg/d | 786 ± 397 | 907 ± 490 | 870 ± 472 | 680 ± 339 | |
| Estimated NEAP range, mEq/d | 1.64, 30.63 | 30.70, 37.43 | 37.59, 45.83 | 45.84, 104.7 | |
| Femoral neck BMD,2g/cm2 | 0.716 ± 0.010 | 0.715 ± 0.010 | 0.717 ± 0.010 | 0.737 ± 0.010 | 0.06 |
| L2-L4 BMD,2g/cm2 | 1.103 ± 0.019 | 1.073 ± 0.020 | 1.088 ± 0.020 | 1.079 ± 0.020 | 0.46 |
1
Values are means ± SD.
2
Values are least-squares means ± SE. Means adjusted for age, height, weight, total energy, physical activity, smoking, alcohol, caffeine, dietary vitamin D, vitamin D supplement use, and, in women, estrogen use.