Skip to main content
. 2011 Feb 2;141(4):588–594. doi: 10.3945/jn.110.135806

TABLE 3.

Total protein and calcium intakes, range of estimated PRAL, and multivariable-adjusted femoral neck and lumbar spine BMD for quartiles of estimated PRAL in Framingham Original Cohort men and women1,2

PRAL quartile
1 2 3 4 P-trend
Men
 n 92 96 98 85
 Total protein1, g/d 62 ± 21 64 ± 22 69 ± 24 83 ± 24
 Total calcium1, mg/d 762 ± 393 704 ± 351 739 ± 380 791 ± 423
 Estimated PRAL range, mEq/d −67.34, −10.73 −10.54, −2.52 −2.50, 5.12 5.16, 25.76
 Femoral neck BMD2, g/cm2 0.889 ± 0.018 0.853 ± 0.017 0.831 ± 0.016 0.859 ± 0.018 0.08
 L2-L4 BMD2, g/cm2 1.292 ± 0.035 1.308 ± (0.034 1.236 ± 0.032 1.295 ± 0.036 0.69
Women
 n 149 148 147 143
 Total protein1, g/d 64 ± 23 63 ± 22 64 ± 25 77 ± 25
 Total calcium1, mg/d 855 ± 431 830 ± 443 801 ± 478 755 ± 386
 Estimated PRAL range, mEq/d −49.20, −12.90 −12.85, −5.22 −5.15, 2.41 2.42, 40.97
 Femoral neck BMD2, g/cm2 0.716 ± 0.010 0.720 ± 0.010 0.722 ± 0.010 0.728 ± 0.010 0.31
 L2-L4 BMD2, g/cm2 1.110 ± 0.020 1.072 ± 0.019 1.079 ± 0.021 1.087 ± 0.020 0.35
1

Values are means ± SD.

2

Values are least-squares means ± SE. Means adjusted for age, height, weight, total energy, physical activity, smoking, alcohol, caffeine, dietary vitamin D, vitamin D supplement use, and in women, estrogen use.