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. 2011 Feb 2;141(4):588–594. doi: 10.3945/jn.110.135806

TABLE 4.

Total protein and calcium intakes, range of estimated NEAP and multivariable-adjusted femoral neck and lumbar spine BMD for quartiles of estimated NEAP in Framingham Offspring men and women1,2

NEAP Quartile
1 2 3 4 P-trend
Men
 n 316 316 319 318
 Total protein,1g/d 69 ± 23 81 ± 27 83 ± 27 90 ± 30
 Total calcium,1mg/d 893 ± 442 884 ± 432 835 ± 453 780 ± 423
 Estimated NEAP range, mEq/d 11.53, 37.87 37.90, 45.68 45.71, 55.12 55.14, 140.1
 Femoral neck BMD,2g/cm2 0.972 ± 0.007 0.970 ± 0.007 0.965 ± 0.007 0.975 ± 0.007 0.86
 L2-L4 BMD,2g/cm2 1.315 ± 0.012 1.313 ± 0.011 1.310 ± 0.011 1.338 ± 0.011 0.17
Women
 n 399 404 403 405
 Total protein,1g/d 66 ± 23 76 ± 25 79 ± 24 85 ± 28
 Total calcium,1mg/d 1200 ± 602 1190 ± 602 1070 ± 516 1000 ± 544
 Estimated NEAP range, mEq/d 6.99, 35.43 35.44, 43.78 43.82, 53.04 53.07, 142.0
 Femoral neck BMD,2g/cm2 0.867 ± 0.006 0.877 ± 0.006 0.865 ± 0.006 0.866 ± 0.006 0.60
 L2-L4 BMD,2g/cm2 1.148 ± 0.009 1.160 ± 0.008 1.147 ± 0.008 1.157 ± 0.009 0.66
1

Values are means ± SD.

2

Values are least-squares means ± SE. Means adjusted for age, height, weight, total energy, physical activity, smoking, alcohol, caffeine, dietary vitamin D, vitamin D supplement use, and in women, menopause status and estrogen use.