Table 4. Results of power analysis for different CAG allele categories used in the logistic regression alongwith the input parameters.
Odds ratio | Pr(Y = 1|X = 1) H0 | α err prob (P-value) | Total sample size | Binomial distribution parameter π | Power (1-β) | |
a CAG RN >19 | 1.56 | 0.34 | 0.05 | 682 | 0.44 | 0.878 |
a BAM≥21 | 2.42 | 0.34 | 0.05 | 341 | 0.18 | 0.997 |
b BAM≥21 | 2.04 | 0.24 | 0.05 | 297 | 0.15 | 0.679 |
c BAM≥21 | 3.14 | 0.16 | 0.05 | 268 | 0.16 | 0.916 |
Pooled RSA cases Vs Controls (For CAG RN, Cases: 2N = 234 Controls: 2N = 448; For BAM, Cases: N = 117 Controls: N = 224).
RSA (2abortions) Vs Controls (Cases: N = 73 Controls: N = 224).
RSA (≥3abortions) Vs Controls (Cases: N = 44 Controls: N = 224).