Table 1. Loss of p53 function is required for anchorage-independent growth of NPM-ALK-expressing conditional Rb-null post-senescent MEFs.
1st infection (P3)(MSCVpuro vector) | 2nd infection (P15–18)(MSCVneo vector) | Number of Foci |
Empty | Empty | 0±0 |
Empty | GSE56 | 0±0 |
NPM-ALK | Empty | 0±0 |
NPM-ALK | GSE56 | 118±11 |
P = passage.