Table 1.

Embryonic dysmorphology after alcohol exposure, scored according to Maele-Fabry et al,1992.

Region	Control	Alcohol	ALC-NTC	ALC-NTO
Allantois	3 ± 0	2.80 ± 0.08	2.86 ± 0.10	2.70 ± 0.14
Branchial bars	2.77 ± 0.09	2.15 ± 0.21	2.17 ± 0.26	2.11 ± 0.39
Brain: Forebrain	4.76 ± 0.10	3.81 ± 0.27*	4.57 ± 0.14	2.29 ± 0.29** ^^
Brain: Midbrain	4.52 ± 0.11	3.71 ± 0.27	4.50 ± 0.14	2.14 ± 0.14** ^^
Brain: Hindbrain	4.71 ± 0.10	3.86 ± 0.24*	4.50 ± 0.14	2.57 ± 0.30** ^^
Caudal Neural Tube	4.76 ± 0.12	4.11 ± 0.19*	4.09 ± 0.26*	4.14 ± 0.26*
Flexion	4.80 ± 0.09	4.33 ± 0.19	4.59 ± 0.19	3.81 ± 0.36*
Heart	4.80 ± 0.10	4.10 ± 0.16**	4.15 ± 0.19*	4.00 ± 0.31*
Limb: Forelimb	2.01 ± 0.06	1.51 ± 0.13**	1.48 ± 0.18*	1.57 ± 0.20
Limb: Hindlimb	0.53 ± 0.10	0.20 ± 0.08*	0.21 ± 0.09	0.19 ± 0.14
Mandibular process	2.08 ± 0.11	1.99 ± 0.09	2.12 ± 0.08	1.71 ± 0.18
Maxillary process	2.41 ± 0.14	2.06 ± 0.16	2.21 ± 0.18	1.76 ± 0.30
Olfactory system	0.47 ± 0.08	0.26 ± 0.08	0.29 ± 0.11	0.20 ± 0.13
Optic system	3.59 ± 0.14	2.87 ± 0.14**	3.02 ± 0.17*	2.57 ± 0.20**
Otic system	3.95 ± 0.12	3.68 ± 0.11	3.88 ± 0.10	3.29 ± 0.18* ^
Somites	4.81 ± 0.09	4.38 ± 0.16	4.50 ± 0.17	4.14 ± 0.34
Total score	53.97 ± 0.66	45.83 ± 1.54**	49.14 ± 1.54**	39.23 ± 1.72** ^^

* P-Value <0.05, ** <0.01; compared to control

^ P-Value <0.05, ^^ <0.01; compared to NTC

Control n = 21; Alcohol (all alcohol-treated, n = 21; ALC-NTC, n = 14; ALC-NTO, n = 7)