Figure 4.

Effect of cyclosporin A on the [Ca²⁺]_M transient induced by high-K⁺ stimulation. Either control cells or cells preincubated for 5 min with 10 μM cyclosporin A were stimulated with a 10-s pulse of medium containing 70 mM K⁺. The figure shows the mean of 11 experiments of each type (bars indicate the SEM of each point). Other details as in Figure 1. For [Ca²⁺]_M calculations, total luminescence was reduced 50%.