Table 1.
Percent CD23+/CD23- cells expressing surface molecules or cytokines after exposure of B cells to EBV
| Subject 1 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 0 hr | 18 hr | 42 hr | 66 hr | 90 hr | 0 hr | 18 hr | 42 hr | 66 hr | 90 hr | |
| CD23+ | CD23- | |||||||||
| CD58 | 1.5 | 14.5 | 59.3 | 50.9 | 81.2 | 30.5 | 45.6 | 64.9 | 57.8 | 59.3 |
| IL6 | 0.5 | 2.5 | 6.8 | 13.5 | 44 | 0.5 | 0.2 | 0.2 | 1.7 | 1.3 |
| CD57 | 1 | 5.4 | 15.8 | 27.3 | 43.2 | 9.7 | 8.2 | 6.5 | 10.3 | 8.3 |
| CD86 | 17.6 | 23.2 | 21.2 | 35.3 | 38.5 | 24.5 | 23.6 | 36.7 | 60.4 | 63.2 |
| MHC CII | 99.9 | 99.6 | 99.5 | 99.7 | 99.9 | 72.2 | 75.1 | 71.8 | 74.8 | 69 |
| PD1 | 14.2 | 10.8 | 8.5 | 9.1 | 6 | 5.6 | 5.6 | 4.8 | 6.1 | 8.6 |
| IL10 | 0.2 | 0.1 | 0.1 | 0.07 | 0.09 | 0.1 | 0.08 | 0.09 | 0.06 | 0.1 |
| Subject 2 | ||||||||||
| CD58 | 1 | 21.5 | 22.1 | 38 | 45.1 | 39.9 | 47.6 | 57.1 | 54.3 | 57.6 |
| IL6 | 0.6 | 1.6 | 2.8 | 14.5 | 20.7 | 0.7 | 1.6 | 0.9 | 0.9 | 0.4 |
| CD57 | 1.4 | 3.5 | 5.3 | 8.9 | 17.7 | 17.6 | 18.2 | 14.9 | 13.7 | 12.5 |
| CD86 | 16.8 | 17.4 | 15.9 | 36.2 | 48.8 | 34.3 | 36.5 | 51.4 | 54.5 | 57.5 |
| MHC CII | 99.4 | 99.1 | 99.2 | 99.3 | 99.7 | 59.2 | 57.2 | 61.7 | 63.4 | 63.8 |
| PD1 | 1.8 | 1.7 | 1.1 | 3.9 | 5.8 | 2.3 | 2.1 | 1 | 1.7 | 2.8 |
| IL10 | 0.1 | 0.1 | 0.1 | 0.04 | 0.2 | 0.03 | 0.04 | 0.04 | 0.05 | 0.08 |