Table 3.
Univariate analyses of prognostic factors for DFS in patients with malignant melanoma
| Factors | Median DFS (months) | P value |
|---|---|---|
| Histological type | ||
| ALM | 20.0 | 0.716 |
| NM | 20.0 | |
| SSM | 28.0 | |
| LMM | 16.0 | |
| MCM | 17.0 | |
| Unclassifiable | 16.0 | |
| Primary location | ||
| Trunk | 25.0 | 0.721 |
| H&N | 16.0 | |
| Palmoplantar/Subungual | 20.0 | |
| Upper/Lower limb | 21.0 | |
| Mucosal | 17.0 | |
| Unkown | 16.0 | |
| Stage | ||
| I | 44.0 | < 0.001 |
| II | 21.0 | |
| III | 13.0 | |
| Gender | ||
| Male | 16.0 | 0.035 |
| Female | 22.0 | |
| Age | ||
| ≤ 65 y | 20.0 | 0.709 |
| > 65 y | 20.0 | |
| Surgery | ||
| Local resection | 15.0 | < 0.001 |
| Extended resection | 24.0 | |
| Ext. resection w/nodal dissection | 13.0 | |
| Adjuvant therapy | ||
| None | 13.0 | < 0.001 |
| Chemotherapy | 20.0 | |
| Chemoradiation | 29.0 | |
| IFN | Not reached | |
| Radiation | 23.0 | |
| Ulceration | ||
| with | 20.0 | 0.488 |
| without | 20.0 | |
| Breslow thickness* | ||
| ≤ 1 mm | 38.0 | 0.178 |
| 1-4 mm | 21.0 | |
| > 4 mm | 13.0 |
*Limited to 180 cases with recorded Breslow thickness