Fig. 1. (A) Structure of L.mexicana LPG (Ilg et al., 1992). The site of the defect caused by the deletion of lpg1 (Huang et al., 1993) and the putative binding sites of anti-phosphoglycan mAbs used in this study (Ilg et al., 1993) are indicated by an arrow and arrowheads, respectively. (B) Alignment of L.mexicana LPG1 with L.donovani LPG1 (Ryan et al., 1993). The putative membrane anchor sequence is underlined, the region similar to mannose-binding proteins boxed and the potential N-glycosylation sites are shaded in grey.