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TrHBMECs (A–C) and HMVECs (D–F) were plated onto Matrigel, and after 18 h were photographed. In A and D the cells were maintained in the presence of control IgG, and both cell types show assembly into tube-like structures. This morphogenesis is inhibited by LM609 antibodies against αvβ3 (B and E) and antibody 2A3 against the α4 laminin chain (C and F). Bar in D, 100 μm.
