Table 1. Representative gene expression changes in E10.5 heads from LOF and GOF mutants compared with wild-type controls.

All values are the mean + standard error for at least n=3 samples using the ABI platform, and all have P<0.05. Positive or negative value indicates the fold-increase or decrease, respectively, compared to wild-type control samples. The dash indicates no significant change. All genes in the Table also showed similar positive or negative gene expression changes on the SAB platform.

Gene	LOF	GOF
Dkk4	− 26 ± 6.7	+ 45.5 ± 5.2
Dkk1	−	+ 8.8 ± 1.0
Wif1	−	+ 7.8 ± 0.9
Fgf4	−	+ 163 ± 6.4
Fgf20	−	+ 17.9 ± 4.3
Fgf9	−	+ 3.3 ± 0.18
Fgf8	−	+ 3.2 ± 0.25