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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Circ Cardiovasc Imaging. 2010 Mar 5;3(3):257–263. doi: 10.1161/CIRCIMAGING.109.911438

Table 2.

Adjusted CMR measures across HOMA-IR quartiles

Men
Models Quartile 1
0.41–2.43†
(n = 176)		 Quartile 2
2.44–3.55†
(n = 174)		 Quartile 3
3.56–5.64†
(n = 168)		 Quartile 4
5.66–57.31†
(n = 132)		 p-value*
LAD, mm Age-adjusted 30 32 32 33 <0.0001
MV-adjusted 31 32 32 31 0.42
LVM/ht2.7, g/m2.7 Age-adjusted 27.1 27.5 27.9 29.7 <0.0001
MV-adjusted 28.8 28.0 27.3 27.6 0.01
LVM/LVEDV gm/ml Age-adjusted 0.85 0.89 0.89 0.97 <0.0001
MV-adjusted 0.87 0.89 0.88 0.94 0.003
RWT Age-adjusted 0.27 0.29 0.28 0.30 0.0004
MV-adjusted 0.28 0.29 0.28 0.29 0.20
CO, L/min Age-adjusted 5.7 5.8 6.0 6.1 0.003
MV-adjusted 6.0 5.9 5.9 5.6 0.17
LVEF (%) Age-adjusted 64 66 66 67 0.0003
MV-adjusted 65 66 66 67 0.009
Women
Models Quartile 1
0.23–2.03†
(n = 216) 		Quartile 2
2.04–2.84†
(n = 213) 		Quartile 3
2.85–4.25†
(n = 208) 		Quartile 4
4.26–43.01†
(n = 175) 		p-value*
LAD, mm Age-adjusted 27 28 28 30 <0.0001
MV-adjusted 29 28 28 28 0.17
LVM/ht2.7, g/m2.7 Age-adjusted 22.6 22.7 23.4 25.6 <0.0001
MV-adjusted 24.1 23.3 23.2 23.2 0.03
LVM/LVEDV gm/ml Age-adjusted 0.77 0.79 0.80 0.83 <0.0001
MV-adjusted 0.78 0.79 0.80 0.81 0.01
RWT Age-adjusted 0.25 0.26 0.26 0.27 0.0009
MV-adjusted 0.25 0.26 0.26 0.26 0.16
CO, L/min Age-adjusted 4.6 4.6 4.9 5.2 <0.0001
MV-adjusted 4.9 4.7 4.9 4.8 0.42
LVEF (%) Age-adjusted 68 69 69 69 0.03
MV-adjusted 68 69 69 69 0.33

Cells present mean values of LV measures;

*

p-value for linear trend;

†

range of HOMA-IR for the respective quartile.

MV-adjusted = multivariable-adjusted; MV model adjusted for age, BMI, systolic blood pressure, cardioactive drug therapy and smoking status.