Figure 11.
Immunohistochemical detection of apoptotic marker Casp-3 and autophagic marker Beclin-1 in LY2 cells under normoxic (control) and hypoxic conditions (CoCl2). Exposure of LY2 cells to hypoxia-mimetic agent (CoCl2; 100µM; 24-hrs) increases the expression of autophagic marker Beclin-1 and not the apoptotic marker Casp-3.