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. 2010 Sep 13;22(3):271–282. doi: 10.1089/hum.2010.059

FIG. 4.

FIG. 4.

(A) Femoral arteries were precontracted with phenylephrine for dose-dependent (10–9–10–3 M) vasorelaxant responses to acetylcholine. Vessels from Ang II-treated Sprague–Dawley treated rats demonstrated a decreased response compared with control rats that was prevented by VECAD-HO-1 transduction. *p < 0.05 versus control, #p < 0.05 versus HO-1, †p < 0.05 versus Ang II+HO-1. (B) 50% effective concentration for acetylcholine. Results are mean ± SE values (n = 6). *p < 0.01 versus control, #p < 0.05 versus Ang II. (C) Artery renal superoxide levels. *p < 0.01 versus control, #p < 0.01 versus HO-1, †p < 0.05 versus Ang II. (D) Artery iNOS expression. Data are shown as mean band density normalized relative to β-actin. *p < 0.05 versus control, #p < 0.05 versus Ang II.