Table 2.
C57-WT | C57-WT + PostC | A1-KO | A1-KO + PostC | B1-KO | B1-KO + PostC | B2-KO | B2-KO + PostC | |
---|---|---|---|---|---|---|---|---|
(n = 8) | (n = 8) | (n = 8) | (n = 7) | (n = 9) | (n = 9) | (n = 7) | (n = 7) | |
At 5 min of Reperfusion | ||||||||
Heart rate, bpm | 368±25 | 339±18 | 336±18 | 362±29 | 360±23 | 308±22 | 341±22 | 347±27 |
Developed force, g | 0.48±0.13 | 0.47±0.14 | 0.53±0.19 | 0.43±0.16 | 0.61±0.15 | 0.58±0.18 | 0.27±0.10 | 0.41±0.14 |
Rate-force product, g×bpm | 182±46 | 168±53 | 178±62 | 168±66 | 216±53 | 195±69 | 85±25 | 158±61 |
At 30 min of Reperfusion | ||||||||
Heart rate, bpm | 345±26 | 309±17 | 324±19 | 321±26 | 288±24 | 301±32 | 354±24 | 334±24 |
Developed force, g | 0.53±0.15 | 0.48±0.13 | 0.55±0.20 | 0.42±0.16 | 0.55±0.14 | 0.59±0.19 | 0.27±0.14 | 0.28±0.09 |
Rate-force product, g×bpm | 190±53 | 151±45 | 172±59 | 143±55 | 148±36 | 164±62 | 85±36 | 103±37 |
Values are Mean±SEM. Abbreviation: bpm – beats per minute. No significant difference was found between the groups for any of the functional parameters (two-way ANOVA with Bonferroni post-hoc test).