Table I.
Characteristics of HTLV-1-infected cell lines.
| In vivo characteristics | ||||||
|---|---|---|---|---|---|---|
| Cells | Origin | Tax expression | Growth | HHM | PTHrP (pM) | MIP-1α (pg/mL) |
| MT-2 | IT | + | s.c., i.m. | – | 5.6 | 19 500 |
| TL | L | − | s.c., i.m., i.p. | – | 3.0 | 280 |
| HT1RV | L + IT | + | Not yet tested | Not yet tested | 6.3 | 5600 |
| C8166 | IT | + | Not yet tested | Not yet tested | 2.9 | 21 600 |
| MT-1 | L | − | Not yet tested | Not yet tested | 4.4 | 3.5 |
| SLB-1 | IT | + | s.c., i.m. | – | 2.8 | 20 600 |
| Hut102 | IT | + | s.c., i.m. | – | 4.8 | 25 100 |
| ED | L | − | s.c., i.m. | – | 3.8 | 3 |
HTLV-1, human T lymphotropic virus type 1; L, leukemic; IT, in vitro transformed; −, negative; +, positive; s.c., subcutaneous; i.m., intramuscular; i.p., intraperitoneal; HHM, humoral hypercalcemia of malignancy; PTHrP, parathyroid hormone-related protein; MIP-1α, macrophage inflammatory protein-1α. Modified from [14].