Table VI.

Analysis of combined outcomes at 1 and 3 years of age^*

	Oral Steroids		Hospitalizations for asthma		Asthma Diagnosis§
	OR [95%CI]	p val	OR [95%CI]	p val	OR [95%CI]	p val
Paternal major depressive episode†	5.66 [1.06, 30.19]	0.04	6.36 [0.33, 123.35]	0.22	1,79 [0.31, 10.48]	0.52
Maternal depressive symptoms‡	1.05 [0.88, 1.26]	0.56	1.26 [1.01, 1.58]	0.04	1.15 [1.00, 1.33]	0.053
Parental depression (linear)	1.51 [0.70, 3.28]	0.29	4.08 [1.14, 14.66]	0.03	1.36 [0.74, 2.48]	0.32

^*Outcomes binary and considered to be positive if child experienced the outcome at both time points, negative if child did not experience the outcome at both time points. Children with outcome at one time point but not at the other were excluded from analysis. All analyses were adjusted for household income, parental asthma, correlation between twins (ETS and gestational age not significant confounders)

^§The combined outcome of asthma diagnosis was defined as physician-diagnosed asthma at age 1 year AND physician-diagnosed asthma at age 3 years plus wheezing in the last year.

^†Paternal model also adjusted for maternal depressive symptoms.

^‡Maternal model also adjusted for paternal depression.