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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Atherosclerosis. 2010 Dec 22;215(1):52–59. doi: 10.1016/j.atherosclerosis.2010.12.009

Table 1.

Prevention of P. gingivalis infection protects mice from plaque accumulation.

Group Immunization Bacterial Infection Plaque area (mm2)
i − − 0.48 ± 0.03*
ii + − 0.53 ± 0.07
iii − + 0.68 ± 0.10*†
iv + + 0.45 ± 0.13†

Plaque area was measured by MRI at the end of the experimental period (25 wks). Plaque area was manually segmented and calculated as follows: plaque area = outer boundary – inner boundary.

*

p < 0.05 between group i and iii,

†

p < 0.01 between group iii and iv, and no significant differences between group i and ii by One-way ANOVA. n = 6 in each group.