Table 2.
Compound | Molecular weight (g·mol−1) | log P | pKa |
---|---|---|---|
Propafenone | 341.44 | 3.93 ± 0.30 | 9.29 ± 0.29 |
GPV005 | 367.48 | 5.00 ± 0.41 | 8.83 ± 0.20 |
GPV009 | 383.52 | 5.12 ± 0.39 | 9.82 ± 0.28 |
GPV019 | 444.57 | 5.48 ± 0.50 | 5.99 ± 0.70 |
GPV031 | 462.56 | 5.57 ± 0.79 | 5.96 ± 0.70 |
GPV062 | 459.58 | 4.49 ± 0.44 | 7.69 ± 0.40 |
GPV180 | 417.54 | 6.24 ± 0.41 | 8.83 ± 0.20 |
GPV574 | 382.50 | 4.10 ± 0.49 | 6.51 ± 0.40 |
GPV576 | 472.62 | 6.40 ± 0.50 | 6.51 ± 0.40 |
GPV929 | 417.54 | 6.24 ± 0.49 | 8.83 ± 0.20 |
SCT-AS03 | 443.58 | 6.09 ± 0.41 | 8.45 ± 0.40 |
Values were calculated using Advanced Chemistry Development (ACD/Laboratories) Software V8.14 (© 1994–2010 ACD/Laboratories, Toronto, Ontario, Canada).