Table 1.

Clinical characteristics and initial laboratory values of the study population. Alkaline phosphatase results are shown as a ratio compared to upper limit of normal range for each assay. Normal ranges for laboratory values were: aspartate aminotransferase 8-48 U/L, total bilirubin 0.1-1 mg/dL, international normalized ratio 0.9-1.2 and albumin 3.5-5 g/dL.

	Patients
	n = 87
Male sex, n (%)	64	( 74 )
Follow-up years*	7.3	(4.5 - 8.9)
Age at diagnosis*	44	(33 - 52)
Symptomatic at diagnosis, n (%)	37	( 43 )
Inflammatory bowel disease, n (%)	66	( 76 )
Biopsy at diagnosis, n (%)	65	( 75 )
Biopsy stage*	2	(1 - 3)
Laboratory values at diagnosis:
Alkaline phosphatase (ULN ratio)*	2.8	(1.8 - 4.6)
AST (U/L)*	74	(44.5 - 125)
Total bilirubin (mg/dL)*	1.1	(0.7 - 1.8)
INR*	1	(0.9 - 1)
Albumin (g/dL)*	4	(3.7 - 4.3)
Initial MELD score*	8	(7 - 10.5)
Initial Mayo risk score*	0.12	(0 - 0.84)

AST, aspartate aminotransferase; INR, international normalized ratio; MELD, model for end-stage liver disease; ULN, upper limit of normal.

^*Median with inter-quartile range included parenthetically.