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. 2011 Mar;18(3):277–285. doi: 10.1177/1933719110386242

Figure 5.

Figure 5.

Adrenocorticotropic hormone (ACTH)-stimulated cortisol production in control (n = 5) and LTH (n = 5) FACs in response to ACTH alone or simultaneous treatment with ACTH and either POMC or 22-kDa pro-ACTH. ACTH treatment significantly increased cortisol production in both groups, which was unaffected by POMC or 22-kDa pro-ACTH (P < .05 compared to basal. LTH indicates long-term hypoxia; FACs, fetal adrenal cortical cells; POMC, proopiomelanocortin.