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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Mol Biochem Parasitol. 2011 Jan 18;177(1):29–34. doi: 10.1016/j.molbiopara.2011.01.004

Fig. 4. yDHODH transgenic PfVP2 knockout parasites are susceptible to the compounds used for other selectable markers.

Fig. 4

Growth inhibition of wild type D10 and ΔVP2::yDHODH transgenic parasites was assessed by standard 3H-hypoxanthine incorporation assay for atovaquone (A), DSM1 (B), WR99210 (C), and blasticidin (D). The calculated IC50 values for these compounds are listed in the Results section. Solid lines, wild type D10 parasites; dashed lines, ΔVP2::yDHODH parasites.