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Comparison of atovaquone and DSM1 selection in P. falciparum D10 and Dd2 strains
| Transfection construct | Strain | Time until appearance of parasite growth (weeks) under selection by: |
|
|---|---|---|---|
| Atovaquone | DSM1 | ||
| pUF-1/ΔMQO | D10 | 8 | 3 |
| Dd2* | no growth | 4 | |
| pUF-1/ΔNDH2 | D10 | 5 | 3 |
| Dd2* | no growth | 3 | |
Selection was carried out in parallel with atovaquone and DSM1. Under atovaquone selection no growth of transfected Dd2 parasites occurred during the length of the experiment (8 weeks).
