Table 3. Prenatal Biomarker Concentrations (μg/L) in Relation to Severity of Social Impairmenta.
Clinical Category (SRS T-Score) | N | LMW Phthalates Median, μg/L(IQR) | HMW Phthalates Median, μg/L(IQR) | N | BPA Median, μg/L(IQR) |
---|---|---|---|---|---|
Normal Range (< 60) | 106 | 328 (147 - 831) | 170 (65 - 362) | 103 | 1.10 (0.50 - 2.10) |
Mild Social Impairment (60–74) | 25 | 460 (224 - 1124) | 159 (92 - 316) | 25 | 1.40 (0.90 - 2.00) |
Severe Social Impairment (≥ 75) | 6 | 1260 (544 - 2863) | 318 (160 - 433) | 6 | 1.45 (1.00 - 2.00) |
IQR = Interquartile Range
Wilcoxon rank-sum tests comparing the medians of mild + severe social impairment versus normal range were not significant. (LMW phthalates, p = 0.09; HMW phthalates, p = 0.54; BPA, p = 0.24).