Table 2.
Comparison of performance of single-modal and multimodal classification methods. The numbers in each bracket denote the minimal and maximal classification rate in 10 independent experiments
| Methods | AD vs. HC |
MCI vs. HC |
||||
|---|---|---|---|---|---|---|
| ACC (%) | SEN (%) | SPE (%) | ACC (%) | SEN (%) | SPE (%) | |
| MRI | 86.2 (82.9-89.0) |
86 (82.7-88.7) |
86.3 (83.1-89.1) |
72.0 (68.4-74.7) |
78.5 (75.6-80.6) |
59.6 (55.1-63.7) |
| CSF | 82.1 (80-84.9) |
81.9 (80-84.7) |
82.3 (80-85.1) |
71.4 (68.2-73.3) |
78 (75.6-79.4) |
58.8 (54.3-61.7) |
| PET | 86.5 (82.9-90.5) |
86.3 (82.7-90.3) |
86.6 (83.1-90.6) |
71.6 (67.4-74.7) |
78.2 (75-80.6) |
59.3 (52.9-63.7) |
|
| ||||||
| Combined | 93.2 (89.0-96.5) |
93 (88.7-96.3) |
93.3 (89.1-96.6) |
76.4 (73.5-79.7) |
81.8 (79.4-84.4) |
66.0 (62.6-70.3) |
| Baseline | 91.5 (88.5-96.5) |
91.4 (88.3-96.3) |
91.6 (88.6-96.6) |
74.5 (71.9-78.2) |
80.4 (78.3-83.3) |
63.3 (59.7-68.3) |
AD = Alzheimer’s Disease, MCI = Mild Cognitive Impairment, HC = healthy control, ACC = classification ACCuracy, SEN = SENsitivity, SPE = SPEcificity