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. Author manuscript; available in PMC: 2012 Feb 2.
Published in final edited form as: Cell Metab. 2011 Feb 2;13(2):160–169. doi: 10.1016/j.cmet.2011.01.003

Figure 6. Chop deletion partially rescues exercise intolerance observed in MKO-PGC-1α mice.

Figure 6

A. MKO-PGC-1α and control mice either with CHOP-null alleles or not were subject to treadmill running till exhaustion as described in Experimental Procedures. Distance was calculated from individual performances. N=15–22 animals per group. ** indicates p <0.01, PGC-1α MKO:CHOP−/− vs. PGC-1α MKO:CHOP+/+. B. Whole blood was collected by cardiac puncture from mice in (A) and serum creatine kinase activity was determined. Data represented means±SEM, * indicates p <0.05 PGC-1α MKO:CHOP−/− vs. PGC-1α MKO:CHOP+/+.