Table 1.
Drugs that Have a Risk of Causing Torsade de Pointes*
| Generic Name | Brand Name(s) |
Clinical Use |
|---|---|---|
| Arsenic trioxide | Trisenox | Cancer/leukemia |
| Bepridil | Vascor | Antianginal |
| Chloroquine | Aralen | Antimalarial |
| Chlorpromazine | Thorazine | Antipsychotic, schizophrenia, antiemetic |
| Cisapride | Propulsid | Gastrointestinal stimulant |
| Clarithromycin | Biaxin | Antibiotic |
| Disopyramide | Norpace | Antiarrhythmic |
| Dofetilide | Tikosyn | Antiarrhythmic |
| Droperidol | Inapsine | Sedative, antiemetic |
| Erythromycin | E.E.S., Erythrocin |
Antibiotic, increase gastrointestinal motility |
| Halofantrine | Halfan | Antimalarial |
| Haloperidol | Haldol | Antipsychotic, schizophrenia, agitation |
| Ibutilide | Corvert | Antiarrhythmic |
| Levomethadyl | Orlaam | Opiate agonist, pain control, narcotic dependence |
| Mesoridazine | Serentil | Antipsychotic, schizophrenia |
| Methadone | Dolophine, Methadose |
Opiate agonist, pain control, narcotic dependence |
| Pentamidine | NebuPent, Pentam |
Antiinfective, pneumocystis pneumonia |
| Pimozide | Orap | Antipsychotic, Tourette tics |
| Procainamide | Pronestyl, Procan |
Antiarrhythmic |
| Quinidine | Quinaglute, Cardioquin |
Antiarrhythmic |
| Sotalol | Betapace | Antiarrhythmic |
| Sparfloxacin | Zagam | Antibiotic |
| Thioridazine | Mellaril | Antipsychotic, schizophrenia |
*
Drugs with low risk and drugs no longer available in the United States are not included in this table. Modified from the Arizona CERT World Wide Web site at www.qtdrugs.org on April 18, 2009.