. 2010 Mar;30(3):217–238. doi: 10.1177/0960327110370982

Table 6.

Properties of the fixed concentration procedure for dusts and mists (R = LC50/TC50 = 50)

LC₅₀ identical for males and females (no gender difference)
Substance				Classification probabilities					Estimated mean no. of animals
LC₅₀		Start concentration	Slope	Class 1	Class 2	Class 3	Class 4	Class 5	Tested	Deaths
0.03		0.05	4	99.9	0.1	0.0	0.0	0.0	1.9	1.6
0.15		0.05	4	3.5	96.5	0.0	0.0	0.0	5.9	0.2
0.70		0.05	4	0.0	99.4	0.6	0.0	0.0	6.0	0.0
1.00		0.50	4	0.0	20.6	79.4	0.0	0.0	6.6	0.6
1.10		0.50	4	0.0	14.1	85.9	0.0	0.0	6.4	0.5
2.50		1.00	4	0.0	0.0	8.2	91.8	0.0	6.2	0.3
10.00		5.00	4	0.0	0.0	0.0	20.6	79.4	6.6	0.6
0.03		0.05	10	100.0	0.0	0.0	0.0	0.0	1.1	1.1
0.15		0.05	10	0.0	100.0	0.0	0.0	0.0	6.0	0.0
0.70		0.05	10	0.0	100.0	0.0	0.0	0.0	6.0	0.0
1.00		0.50	10	0.0	0.1	99.9	0.0	0.0	6.0	0.0
1.10		0.50	10	0.0	0.0	100.0	0.0	0.0	6.0	0.0
2.50		1.00	10	0.0	0.0	0.0	100.0	0.0	6.0	0.0
10.00		5.00	10	0.0	0.0	0.0	0.1	99.9	6.0	0.0
LC50 for females 10 times greater than LC50 for males
LC50 (M)	LC50 (F)
0.03	0.30	0.05	4	0.1	99.9	0.0	0.0	0.0	6.0	0.0
0.15	1.50	0.05	4	0.0	81.9	18.1	0.0	0.0	6.2	0.0
0.70	7.00	0.05	4	0.0	0.6	98.1	1.3	0.0	7.0	0.0
1.00	10.00	0.50	4	0.0	0.0	94.4	5.6	0.0	6.1	0.0
1.10	11.00	0.50	4	0.0	0.0	92.3	7.7	0.0	6.1	0.0
2.50	25.00	1.00	4	0.0	0.0	0.0	88.6	11.4	6.1	0.0
10.00	100.00	5.00	4	0.0	0.0	0.0	0.0	100.0	6.0	0.0
0.03	0.30	0.05	10	0.0	100.0	0.0	0.0	0.0	6.0	0.0
0.15	1.50	0.05	10	0.0	98.7	1.3	0.0	0.0	6.0	0.0
0.70	7.00	0.05	10	0.0	0.0	100.0	0.0	0.0	7.0	0.0
1.00	10.00	0.50	10	0.0	0.0	100.0	0.0	0.0	6.0	0.0
1.10	11.00	0.50	10	0.0	0.0	100.0	0.0	0.0	6.0	0.0
2.50	25.00	1.00	10	0.0	0.0	0.0	99.9	0.1	6.0	0.0
10.00	100.00	5.00	10	0.0	0.0	0.0	0.0	100.0	6.0	0.0

LC₅₀, median lethal concentration.