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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2010 Nov 13;4(1):87–93. doi: 10.1161/CIRCEP.110.959726

Figure 6.

Figure 6

Meta-analysis of promoter B and A SNPs for association with early onset lone AF. Meta-analyses of the results (additive genetic model) from the three cohorts were performed using a fixed effect model. Promoter SNP B (top), but not promoter SNP A (bottom), was significantly associated with early onset lone AF. Grey boxes reflect the weighting (W), based on sample size, of each cohort in the meta-analysis. MAF, minor allele frequency for cases/controls; OR, odds ratio for lone AF with each additional copy of minor allele; CI, confidence interval. *denotes P<0.05.