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. Author manuscript; available in PMC: 2011 Mar 15.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Oct 1;29(12):2182–2190. doi: 10.1161/ATVBAHA.109.192740

Table 2.

Age-adjusted incidence rates of sudden cardiac death, non-sudden cardiac death, and non-fatal myocardial infarction in tertiles of markers of inflammation and hemostasis, the ARIC cohort study

Marker/Range Sudden cardiac death (n=207) Non-sudden cardiac death (n=174) Non-fatal MI (n=737)
Events p-years IR per 10,000
(95% CI)
Events p-years IR per 10,000
(95% CI)
Events p-years IR per 10,000
(95% CI)
Von Willebrand factor (%)
 <92 33 61,580 6.1 (3.9, 8.2) 32 61,580 6.1 (4.0, 8.3) 210 60,390 36.7 (31.8, 41.7)
 92-129 55 59,014 9.4 (6.9, 11.9) 51 59,014 8.6 (6.3, 11.0) 225 57,882 38.0 (33.2, 42.9)
 >129 119 56,667 19.8 (16.2, 23.4) 91 56,667 14.9 (11.8, 18.0) 302 55,215 51.1 (45.5, 56.8)
Factor VIIIc (%)
 <112 38 62,334 7.0 (4.7, 9.2) 44 62,334 8.2 (5.8, 10.7) 227 61,018 38.7 (33.7, 43.7)
 112-141 52 58,986 8.9 (6.5, 11.3) 34 58,986 5.7 (3.8, 7.6) 220 57,922 37.2 (32.4, 42.0)
 >141 117 55,941 19.9 (16.2, 23.5) 96 55,941 16.2 (12.9, 19.4) 290 54,547 49.6 (44.0, 55.2)
Fibrinogen (μmol/L)
 <7.97 38 62,181 6.7 (4.5, 8.8) 34 62,181 6.2 (4.1, 8.4) 149 61,354 25.1 (21.0, 29.1)
 7.97-9.41 45 57,909 7.7 (5.4, 9.9) 47 57,909 8.2 (5.8, 10.5) 250 56,743 43.0 (37.9, 48.2)
 >9.41 124 57,171 21.0 (17.3, 24.8) 93 57,171 15.8 (12.6, 19.0) 338 55,390 57.9 (51.9, 63.9)
WBC (x10−6)
 ≤5.1 54 61,309 9.1 (6.7, 11.5) 27 61,309 4.5 (2.8, 6.2) 169 60,472 27.8 (23.7, 31.9)
 5.1-6.1 32 43,872 7.3 (4.8, 9.9) 31 43,872 6.9 (4.5, 9.4) 158 43,075 35.8 (30.4, 41.3)
 ≥6.1 121 72,081 16.9 (13.9, 20.0) 116 72,081 16.2 (13.3, 19.2) 410 69,941 57.5 (52.1, 62.8)
Albumin (g/L)
 <38 120 78,903 14.9 (12.2, 17.5) 107 78,903 13.4 (10.9, 16.0) 351 77,051 44.2 (39.7, 48.7)
 38-40 55 52,963 10.7 (7.8, 13.5) 42 52,963 8.0 (5.6, 10.5) 216 51,967 41.2 (35.8, 46.5)
 >40 32 45,395 7.1 (4.6, 9.6) 25 45,395 6.0 (3.6, 8.4) 170 44,469 38.7 (32.9, 44.4)