FIG. 2.

Phylogenetic comparison of the HWE-HK family with representatives of the previously described HK families. The tree was generated by using the predicted HK domain by the ClustalX neighbor-joining method. The bar represents a branch length equivalent to 0.1 amino acid change per residue. The bracket on the right identifies representatives of the 11 previously defined HK families (gray lines). Black lines indicate the 81 representatives of the HWE HK family. Arrowheads and circles identify members with GAF-phy and potential chemotaxis methyltransferase sensor domains, respectively, upstream of the HK domain. The asterisks identify members of the HWE-HK family from A. tumefaciens. Abbreviations are as defined in the legend to Fig. 1.