TABLE 3.

Spearman's correlation coefficients for maternal dietary fatty acid intake and fatty acid concentrations in maternal and cord blood in 1250 mother-child pairs in Project Viva¹

	Midpregnancy maternal dietary intake
	Total n−3 PUFAs	DHA + EPA	Total n−6 PUFAs	AA	Total n−6:n−3 ratio	AA:DHA + EPA ratio	Fish intake
Fatty acid intake in maternal midpregnancy diet (n = 1250)
Total n−3 PUFAs	1.0	0.32***	0.76***	0.39***	−0.69***	−0.21***	0.29***
DHA + EPA		1.0	−0.01	0.36***	−0.51***	−0.94***	0.84***
Total n−6 PUFAs			1.0	0.21***	−0.10**	0.08*	0.00
AA				1.0	−0.34***	−0.06dagger	0.29***
Total n−6:n−3 ratio					1.0	0.43***	−0.45***
AA:DHA + EPA ratio						1.0	−0.80***
Fatty acid concentrations in maternal midpregnancy plasma (n = 227)
Total n−3 PUFAs	0.17 *	0.50***	0.03	0.07	−0.25***	−0.50***	0.47***
DHA + EPA	0.15*	0.50***	0.00	0.09	−0.24***	−0.51***	0.48***
Total n−6 PUFAs	0.21**	0.16*	0.25***	0.12dagger	−0.03	−0.14*	0.09
AA	0.02	0.06	0.00	0.12dagger	−0.01	0.00	0.01
Total n−6:n−3 ratio	−0.10	−0.47***	0.06	−0.03	0.25***	0.47***	−0.46***
AA:DHA + EPA ratio	−0.14*	−0.50***	0.01	0.03	0.25***	0.56***	−0.51***
Fatty acid concentrations in umbilical cord plasma (n = 3022)
Total n−3 PUFAs	0.13dagger	0.37***	−0.07	0.09	−0.27***	−0.34***	0.32***
DHA + EPA	0.13dagger	0.36***	−0.08	0.08	−0.27***	−0.33***	0.32***
Total n−6 PUFAs	0.06	−0.03	0.15*	0.10dagger	0.03	0.06	−0.06
AA	0.00	−0.14*	0.03)	0.05	0.01	0.17*	−0.11dagger
Total n−6:n−3 ratio	−0.12dagger	−0.40***	0.12dagger	−0.06	0.29***	0.38***	−0.36***
AA:DHA + EPA ratio	−0.14dagger	−0.45***	0.09	−0.07	0.28***	0.44***	−0.39***
3-y fish intake	0.09**	0.34***	−0.05	0.14***	−0.20***	−0.32***	0.33***

¹PUFA, polyunsaturated fatty acid; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; AA, arachidonic acid. ***P <0.001, **0.001 ≤ P < 0.01, *0.01 ≤ P < 0.05, ^†0.05 ≤ P < 0.10.

²n = 246 for total n−3, EPA, DHA + EPA, n−6:n−3 ratio, and AA:DHA + EPA ratio from cord blood plasma.