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Locomotor activity of animals in the various experimental groups. Open field was used to assess (A) horizontal activity (number of beam breaks), (B) time spent in the peripheral zone (seconds) and (C) time spent in the central zone (seconds). **p < 0.01 SI compared to C rats. Data are presented in mean ± SEM. (C: n = 4; SS: n = 6; and SI: n = 6).
