Table 1.

Enzyme Inhibition Data for Substituted Benzimidazoles^a

compd	X	% inhibitionb (1 μM)
(A) 5, 6, or 7-Methyl-Substituted
1-(2,6-Difluorobenzyl)-2-(2,6-difluorophenyl)benzimidazoles
2	H	50
1	4-CH3	71
41	5-CH3	22
42	6-CH3	42
43	7-CH3	1
45	4,5-diCH3	26
46	4,6-diCH3	37
(B) 4, 5, or 6-Substituted
1-(2,6-Difluorobenzyl)-2-(2,6-difluorophenyl)benzimidazoles
54	4-Br	78
38	5-Br	43
55	4-Cl	75
39	5-Cl	48
40	6-Cl	69
48	4-NO2	51
49	5-NO2	30

^aEnzyme assays done with WT RT.

^b% inhibition is the average of two experiments done in triplicate.