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. Author manuscript; available in PMC: 2011 Jul 6.
Published in final edited form as: Nature. 2010 Nov 28;469(7328):102–106. doi: 10.1038/nature09603

Figure 5. Myelination, brain size, and olfactory function following telomerase reactivation.

Figure 5

(a) Representative brains from age-matched experimental and control animals; (b) brain weights, n≥10, ***p=0.0004, *p=0.02; (c) representative electron micrographs of myelinated axonal tracts in CC; arrow heads indicate myelin sheath width (12,000X); scale bars=200nm; (d) g ratios (inner/outer radii) (n=2, >150 axons/mouse) ***p<0.0001; (e) representative tracings of experimental and control mice during 3-minute exposure to water or 2-MB. (f, g) Time spent in scent zone with water or 2-MB for vehicle- or 4-OHT-treated G0TERT-ER (squares) and G4TERT-ER (circles) mice; n=4. Error bars represent s.d., except in (d)(s.e.m.).