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Enthalpy-entropy compensation plots for the binding of allosteric effectors to Kinesin-5 motor domains. The plots for STC (A) and monastrol (B) binding have slopes of 1.12 and 1.04, respectively. Motors shown include HsEg5 (square), Klp61F-L5-α3 (circle), and Klp61F-L5 (triangle).
