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. 2000 Nov 1;19(21):5650–5660. doi: 10.1093/emboj/19.21.5650

graphic file with name cdd558f8.jpg

Fig. 8. Close-up stereoview comparing the interactions of the C-terminal tails of haemadin (red) and hirudin (green) with the fibrinogen-recognition exosite of a neighbouring thrombin molecule (blue) (see text for details). Side chains of interacting thrombin/inhibitor residues are labelled explicitly. Notice the close agreement between the phenyl moieties of Phe47I and Phe56H; also the side chain pairs Phe50I–Ile59H and Glu48I–Glu57H occupy similar positions.

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