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| Mutant | Ki × 1013 (M) | Fold increase compared to native |
|---|---|---|
| Native | 2.435 ± 0.138 | 1.00 |
| Arg73Glu | 3.365 ± 0.523 | 1.38 |
| Arg93Glu | 24.081 ± 0.119 | 9.89 |
| Lys149EGlu | 2.337 ± 0.347 | 0.96 |
| Arg233Glu | 7.333 ± 0.448 | 3.01 |
| Lys236Glu | 4.221 ± 0.302 | 1.73 |
| Lys240Glu | 12.905 ± 0.872 | 5.30 |
