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Effect of apo-10′-lycopenoic acid on the nuclear accumulation of Nrf2. (a) BEAS-2B cells were treated with 10 μM of apo-10′-lycopenoic acid for indicated time. (b) BEAS-2B cells were treated with indicated concentration of apo-10′-lycopenoic acid for 6 hr. Nuclear proteins were extracted and nuclear Nrf2 was detected by Western blot and analyzed with an imaging densitometer. The data are representative results of at least 3 independent experiments.
