Table 4. Odds ratios regarding fertility by histological subtype.
Nonseminoma | Seminoma | ||||
---|---|---|---|---|---|
Controls | Cases | OR (95% CI) | Cases | OR (95% CI) | |
Fertility Distress | |||||
Yes | 6 | 22 | 6.77 (2.38-19.23) | 10 | 1.61 (0.76-8.94) |
No | 155 | 60 | 1.0 | 58 | 1.0 |
P-value | 0.0003 | 0.13 | |||
Difficulty in Fathering Children | |||||
Yes | 8 | 30 | 6.55 (2.61-16.41) | 18 | 4.49 (1.57-12.87) |
No | 136 | 56 | 1.0 | 42 | 1.0 |
P-value | <0.0001 | 0.0051 | |||
Tested for Infertility | |||||
Yes | 8 | 23 | 3.56 (1.41-8.97) | 15 | 4.20 (1.48-11.90) |
No | 210 | 96 | 1.0 | 87 | 1.0 |
P-value | 0.0071 | 0.0070 | |||
Person Tested | |||||
Man | 4 | 7 | 2.21 (0.53-9.13) | 8 | 2.83 (0.65-12.31) |
Woman | 3 | 1 | 0.54 (0.054-5.32) | 0 | 0.001 (inf.) |
Both | 6 | 18 | 4.40 (1.59-12.16) | 8 | 2.79 (0.80-9.71) |
None | 76 | 44 | 1.0 | 34 | 1.0 |
P-trend | 0.074 | 0.27 | |||
Fathered Children | |||||
Yes | 45 | 55 | 1.85 (1.12-3.05) | 23 | 0.80 (0.42-1.52) |
No | 178 | 75 | 1.0 | 88 | 1.0 |
P-value | 0.016 | 0.51 | |||
# Children Fathered | |||||
0 | 178 | 75 | 1.0 | 88 | 1.0 |
1 | 27 | 28 | 1.98 (1.04-3.78) | 12 | 1.01 (0.42-2.43) |
2 | 11 | 17 | 2.85 (1.22-6.68) | 8 | 1.46 (0.43-4.96) |
3+ | 7 | 10 | 2.43 (0.81-7.24) | 3 | 1.76 (0.37-8.33) |
P-trend | 0.037 | 0.42 |
All models adjusted by BMI, income, age, smoking status, race, and low sperm count