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Co-localization of MMP-2 and titin near the Z-disc in diseased human heart. Left ventricle sections were used from the explanted failing heart from a patient receiving a heart transplant. a-d shows that high density of MMP-2 (green) co-localizes (yellow) with T12 epitope (red) at the Z-lines. e-h shows that low density of MMP-2 (red) co-localizes (yellow) with M8 epitope (green) at M-lines. BF (bright field images). Scale bar is 10 μm.
