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. Author manuscript; available in PMC: 2012 Mar 15.
Published in final edited form as: Mutat Res. 2011 Feb 16;708(1-2):21–27. doi: 10.1016/j.mrfmmm.2011.01.002

Figure 2.

Figure 2

The transcription levels of ERCC1 in UV20ERCC1_C and UV20ERCC1_T cell lines remained the same upon cisplatin treatment. There is no difference in ERCC1 transcripts in the cells transfected with either C or T allele before treatment (p=0.495). ERCC1 transcription increased in both cell lines 30 minutes after cisplatin treatment. This increase in transcription peaked at 4 hours following cisplatin induction. However, there was no significant difference in ERCC1 gene expression levels between the two transfected cell lines, UV20ERCC1_C and UV20ERCC1_T (p=0.1737). Results are obtained from 4 independent experiments with duplicates in each experiment.