Table 4.
Subjective scores that were significantly different from HC and CFS+MA (mean [95% C.I.]; probability).
| Cohort 1 | Cohort 2 | ||||||
|---|---|---|---|---|---|---|---|
| HC | CFS | HC | All CFS | CFS+MO | CFS+MA | CFS+T | |
| Headache Severity Score | 0.85 [0.69-1.01] N = 191 |
2.64 [2.45-2.83] n = 152 p < 10-10 * |
0.55 [0.11-0.99] n = 20 |
2.63 [2.33-2.93] n = 63 p < 10-9 ** |
2.76 [2.39-3.13] n = 38 p < 10-8 ** |
2.93 [2.43-3.43] n = 14 p = 10-6 ** |
1.82 [1.08-2.56] n = 11 p = 0.03 ** |
| McGill Sensory Score | 6.5 [5.2-8.8] n = 109 |
8.8 [7.0-10.5] n = 55 p = 0.002 * |
4.3 [0.9-7.7] n = 18 |
13.9 [11.5-16.3] n = 44 p = 0.0004** |
13.6 [10.5-16.6] n = 24 p = 0.002** |
17.5 [11.6-23.4] n = 12 p = 0.002 ** |
9.50 [7.0-12.0] n = 8 |
| Neuro-Construct | 2.39 [1.58-3.20] n = 57 |
7.00 [4.91-9.01] n = 21 p = 0.000005* |
1.71 [0.36-3.06] n = 17 |
7.08 [5.93-8.23] n = 48 p = 0.00003** |
6.33 [4.92-7.74] n = 30 p = 0.0007** p = 0.002*** |
11.4 [10.3-12.5] n = 10 p = 10-8 ** |
4.50 [2.84-6.16] n = 8 p = 0.00002*** |
| Cardio-Construct | 1.46 [0.79-2.13] n = 57 |
2.86 [1.45-4.27] n = 21 p = 0.053 |
0.76 [-0.07-1.59] n = 17 |
3.22 [2.30-4.14] n = 45 p = 0.02** |
2.70 [1.67-3.73] n = 27 p = 0.045*** |
5.90 [3.55-8.25] n = 10 p = 0.0004 ** |
1.63 [0.65-2.61] n = 8 p = 0.049 *** |
* vs. HC of Cohort 1; ** vs. HC of Cohort 2; and *** vs. CFS+MA using 2-tailed unpaired Student's t-tests with Bonferroni corrections after ANOVA. Neuro-Construct = sum of scores for poor memory, dizziness, balance problems, and numbness in arms or legs. Cardio-Construct = sum of scores for rapid heart rate, irregular heart rate, palpitations, and chest pain.