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. 2011 Mar 15;6(3):e17978. doi: 10.1371/journal.pone.0017978

Table 5. Estimated frequency of common haplotypes and their associations with significant coronary artery disease with respect to the presence of T2DM.

Non-diabetic patients Diabetic patients
Haplotype CAD (−) % CAD (+) % OR [95%CI] P value CAD (−) % CAD (+) % OR [95%CI] P value
rs7903146 C>T rs12255372 G>T rs11196205 G>C
C G G 53.1 54.6 1.06 [0.91–1.24] 0.468 55.6 45.8 0.67 [0.50–0.90] 0.009
C G C 15.6 13.7 0.86 [0.69–1.08] 0.193 11.8 12.0 1.03 [0.65–1.62] 0.908
C T C 1.9 1.0 0.53 [0.26–1.01] 0.050 2.8 2.4 0.86 [0.34–2.21] 0.755
T G C 3.5 3.5 1.01 [0.65–1.54] 0.983 4.6 3.0 0.66 [0.31–1.42] 0.286
T T C 25.2 26.7 1.08 [0.90–1.29] 0.410 24.3 35.1 1.67 [1.19–2.22] 0.003

ORs (odds ratios), 95%CIs (confidence intervals), and p values were calculated by chi-squared tests by comparing each haplotype to all remaining haplotypes. CAD indicates coronary artery disease.