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Efficacy of antiviral drugs against Korean echovirus 5
| Compounds | IC50a | CC50b | TIc |
|---|---|---|---|
| Azidothymidine | NDd | >100 | - |
| Acyclovir | NDd | >100 | - |
| Amantadine | 1 ± 0.42 | >100 | 100 |
| Lamivudine | NDd | >100 | - |
| Ribavirin | 22 ± 1.36 | >100 | 4.55 |
These results are the mean ± S.D. (n = 3)
a Concentration of compound in μg/mL producing 50% inhibition of virus-induced cytopathic effects.
b The 50% cytotoxic concentration for target cells in μg/mL.
C Therapeutic index (TI) = CC50/IC50
d Not Determined
