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. Author manuscript; available in PMC: 2012 Mar 15.
Published in final edited form as: Biol Psychiatry. 2011 Mar 15;69(6):508–509. doi: 10.1016/j.biopsych.2011.01.017

Figure 1.

Figure 1

Hippocampal FGF2 levels are correlated with events that mediate allostatic load for anxiety and mood disorder morbidity. Genetic predisposition, prenatal and postnatal environmental events all contribute to any given individual’s allostatic load, and, in addition, they may also modulate hippocampal FGF2 levels. FGF2 modulates allostatic load through unknown factors, which might include hippocampal neurogenesis, gliogenesis and synaptogenesis, all of which have been implicated in the regulation of learning and memory, and perhaps in certain aspects of ADT.