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. Author manuscript; available in PMC: 2012 Mar 17.

Published in final edited form as: Cell Host Microbe. 2011 Mar 17;9(3):212–222. doi: 10.1016/j.chom.2011.02.006

A) bmDC were cultured from WT and wrt mice. Eight million bmDC were adoptively transferred i.v. into 8–10wk old recipient WT B6 mice. Either 1 hour after, or 2 days prior to infection with 2×10⁶ pfu LCMV Cl13, bmDC were adoptively transfered to recipient B6 mice. Serum was harvested and titered at the indicated times. Mean and SEM from 8 mice/group are shown. B) wrt bmDC have higher levels of MHC molecules (class I and class II) and costimulatory molecules (CD80 and CD86). Flow cytometric analysis of bmDC from WT and wrt mice are shown with Mean and SEM for both % of cells in highly activated gate as well as gMFI for MHC and costimulatory molecules from one of 2 similar independent experiments (N=4). *=P-value<0.05.

A) bmDC were cultured from WT and wrt mice. Eight million bmDC were adoptively transferred i.v. into 8–10wk old recipient WT B6 mice. Either 1 hour after, or 2 days prior to infection with 2×10⁶ pfu LCMV Cl13, bmDC were adoptively transfered to recipient B6 mice. Serum was harvested and titered at the indicated times. Mean and SEM from 8 mice/group are shown. B) wrt bmDC have higher levels of MHC molecules (class I and class II) and costimulatory molecules (CD80 and CD86). Flow cytometric analysis of bmDC from WT and wrt mice are shown with Mean and SEM for both % of cells in highly activated gate as well as gMFI for MHC and costimulatory molecules from one of 2 similar independent experiments (N=4). *=P-value<0.05.