. Author manuscript; available in PMC: 2012 Mar 17.

Published in final edited form as: Cell Host Microbe. 2011 Mar 17;9(3):212–222. doi: 10.1016/j.chom.2011.02.006

Table 1. Mbtps1^wrt are immunodeficient when challenged with LCMV Armstrong.

Diet and dpi are indicated for ex vivo peptide stimulation assay, cytotoxic killing assay and anti-LCMV antibody titers.

Diet	Parameter	Mbtps1 ^WT/WT	Mbtps1 ^Wrt/WT	Mbtps1 ^Wrt/Wrt	Mbtps1^Wrt/Wrt + 5% + cholesterol diet
Primary response
Regular	7dpi %IFNγ⁺np396⁺CD8⁺	6±1	7±3	0.4±3	n.d.^*
Regular	7dpi %IFNγ⁺gp33⁺CD8⁺	2±1	2±0.6	0.4±0.2	n.d.^*
Cholesterol	7dpi specific cytotoxic activity	n.d.	57	8	39^*
Cholesterol	28dpi anti-LCMV antibodies	n.d.	860	263	643^*
Secondary response
Regular	74dpi %IFNγ⁺np396⁺CD8⁺	5±1	12±3	7±0.2	n.d.
Regular	74dpi %IFNγ⁺gp33⁺CD8⁺	4±0.8	5±0.4	4±1	n.d.

P-value<0.05.

Table 1. Mbtps1wrt are immunodeficient when challenged with LCMV Armstrong.